Biobank Lifespan

Tools - analysis by external researchers

This website presents the ACCE Model Process for Evaluating Genetic Tests, which includes 1) Analytic validity of the test; 2) Clinical validity of the test; 3) Clinical utility of the test to improve patient outcomes; 4) Ethical, legal, and social issues that may arise in the context of using th
This website provides access to public databases and bioinformatic tools. NCBI conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information.
The ESPRESSO project and the DataSHIELD project develop statistical methods for meta-analysis of large scale studies.
This website provides access to public databases and bioinformatic tools. The resource includes data on nucleic acid and protein sequences and macromolecular structures.
This website provides access to automated analysis of statistical power for variance components (VC), quantitative trait locis (QTL) linkage and association tests in sibships, and other common tests.
This website presents this project which has undertaken a global analysis of polymorphism patterns and of linkage disequilibrium across the human genome.
This website lists and describes genetic association studies. Studies can be searched by phenotypes, genetic markers, or results of interest. Study designs and results can be compared using the browser tool. It is maintained by a team led by Professor Anthony Brookes.
Using the same outline as the STROBE statement, STREGA introduces concepts that are of particular interest in genetic association studies such as genotyping error, population stratification, modelling haplotype variation, Hardy-Weinberg equilibrium, and replication.
This website presents the EGAPP™ (Evaluation of Genomic Applications in Practice and Prevention) project whose main goal is to establish and test a systematic, evidence-based process for evaluating genetic tests and other applications of genomic technology that are in transition from research to
This website displays an archive of the results of genetic association studies of complex human diseases and disorders.
This website, from Gonçalo Abecasis' research group, emphases on developing computational and statistical software required for understanding human genetic variation, with a particular focus on complex human disease and encompassing both linkage and association analysis.
This website provides information about, and access to software for, applications in Bayesian and computational statistics particularly in population genetics.
PEDSYS is a database system developed to provide a software environment in which to manage and analyse genetic and demographic data, particularly in relation to pedigree (family-based) data. The system supports integrated collection, management and analysis of constantly evolving data sets.
This website is a repository of software dealing with: genetic linkage analysis for human pedigree data, QTL analysis for animal/plant breeding data, genetic marker ordering, genetic association analysis, haplotype construction, pedigree drawing, population genetics and TDT (such as TaggerExterna
This website presents protocols and software for identifying, genotyping, and modeling the associations between single nucleotide polymorphisms (SNPs) in candidate genes and pathways that underlie inflammatory responses in humans.
This software computes an optimal array of tag SNPs to capture a set of SNPs of scientific interest, based on pairwise linkage disequilibrium that takes into account practical needs and constraints faced by investigators.
This website contains the reference sequence and working draft assemblies for a large collection of genomes and several tools are available such as In Silico PCRExternal, ProteomeExternal and Genome BrowsersExternal. It also provides a portal to the ENCODE projectExternal.